Prediction of Complex Traits: Robust Alternatives to Best Linear Unbiased Prediction
نویسندگان
چکیده
منابع مشابه
Prediction of Complex Human Traits Using the Genomic Best Linear Unbiased Predictor
Despite important advances from Genome Wide Association Studies (GWAS), for most complex human traits and diseases, a sizable proportion of genetic variance remains unexplained and prediction accuracy (PA) is usually low. Evidence suggests that PA can be improved using Whole-Genome Regression (WGR) models where phenotypes are regressed on hundreds of thousands of variants simultaneously. The Ge...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2018
ISSN: 1664-8021
DOI: 10.3389/fgene.2018.00195